.rama-app{margin-top:28px;padding:24px;background:var(--panel);border:1px solid var(--line);border-radius:12px}.rama-app h3{font-size:22px}.rama-app h4{font-size:17px;font-weight:600}.rama-metrics{display:flex;gap:12px;flex-wrap:wrap;margin:18px 0}.rama-metric{border:1px solid var(--line);padding:13px 20px;min-width:125px;border-radius:8px}.rama-metric strong{display:block;font:30px/1.1 var(--mono);color:var(--accent)}.rama-metric span{font:11px var(--mono);color:var(--muted)}.rama-controls{display:flex;gap:10px;align-items:center;flex-wrap:wrap}.rama-controls .helper{margin-right:auto}.rama-main-grid{display:grid;grid-template-columns:minmax(0,1.1fr) minmax(0,1fr);gap:18px;margin-top:20px;align-items:start}.rama-column{display:grid;gap:18px;min-width:0}.rama-panel{background:var(--paper);border:1px solid var(--soft);border-radius:8px;padding:20px;min-width:0}.rama-panel-head{display:flex;align-items:baseline;justify-content:space-between;gap:15px;margin-bottom:12px}.rama-panel-head .label{color:var(--muted)}#rama-plot,#rama-histogram{display:block;width:100%;height:auto;overflow:visible}#rama-plot{touch-action:none;user-select:none}.plot-bg{fill:var(--panel);stroke:var(--line);stroke-width:1}.plot-grid{stroke:var(--soft);stroke-width:1}.plot-zero{stroke:var(--line);stroke-width:1;stroke-dasharray:4 4}.plot-tick{fill:var(--muted);font:11px var(--mono)}.plot-axis{fill:var(--ink);font:12px var(--mono)}.residue-point{stroke:var(--paper);stroke-width:1.5;cursor:pointer}.residue-point.is-selected{fill:var(--accent)}.residue-point.is-muted{fill:var(--link);opacity:.25}.residue-point:hover,.residue-point:focus{stroke:var(--ink);stroke-width:3;outline:none}.brush-rect{fill:var(--accent);fill-opacity:.16;stroke:var(--accent);stroke-width:1.5;pointer-events:none}.plot-key{display:flex;flex-wrap:wrap;gap:17px;font:11px var(--mono);color:var(--muted);margin:6px 0 12px}.key-dot{display:inline-block;width:8px;height:8px;border-radius:50%;background:var(--accent);margin-right:7px}.key-dot.muted{background:var(--link);opacity:.4}.hist-total{fill:var(--link);opacity:.3}.hist-picked{fill:var(--accent)}.hist-target{cursor:pointer}.hist-target:hover,.hist-target:focus{outline:none;filter:brightness(1.2)}.hist-target:focus .hist-total{stroke:var(--ink);stroke-width:2}.rama-sequence{display:grid;grid-template-columns:repeat(10,minmax(0,1fr));gap:4px;margin:15px 0 10px}.sequence-letter{display:flex;align-items:center;justify-content:center;min-height:36px;border:1px solid var(--line);background:transparent;font:15px var(--mono);padding:4px;color:var(--ink)}.sequence-letter.is-selected{border-color:var(--accent);color:var(--accent);background:var(--panel)}.sequence-letter.is-muted{opacity:.4}.motif-form{display:flex;gap:8px;margin-top:18px}.motif-form input{min-width:0;flex:1;background:var(--panel);color:var(--ink);border:1px solid var(--line);padding:9px 12px;font:15px var(--mono);text-transform:uppercase}.motif-examples{display:flex;gap:7px;margin:12px 0;flex-wrap:wrap}.motif-examples button,.motif-match{background:transparent;border:1px solid var(--line);border-radius:20px;color:var(--link);font:12px var(--mono);padding:7px 11px;min-height:34px}#motif-matches{display:flex;flex-wrap:wrap;gap:7px;margin-top:10px}.table-scroll{max-height:350px;overflow:auto;margin-top:14px;border:1px solid var(--soft);border-radius:5px}.residue-table{width:100%;border-collapse:collapse;font:12px/1.6 var(--mono)}.residue-table th{position:sticky;top:0;background:var(--paper);z-index:1;text-align:left;color:var(--muted);font-weight:400;padding:9px 8px;border-bottom:1px solid var(--line)}.residue-table td{padding:6px 8px;border-bottom:1px solid var(--soft);white-space:nowrap}.row-selected{background:var(--panel)}.row-muted{opacity:.4}.residue-table input{accent-color:var(--accent);width:17px;height:17px}.table-residue{border:0;background:transparent;color:var(--ink);font:12px var(--mono);padding:4px 0;text-decoration:underline;text-underline-offset:3px}.rama-trail{margin-top:18px}.trail-layout{display:grid;grid-template-columns:1.2fr 1fr;gap:22px;margin-top:20px}.trail-list{list-style:none;max-height:320px;overflow:auto;padding:0;margin:18px 0 0}.trail-entry{margin:0}.trail-entry button{display:flex;gap:14px;width:100%;text-align:left;background:transparent;color:var(--ink);border:0;border-left:2px solid var(--line);padding:12px 14px}.trail-entry.is-current button{border-left:3px solid var(--accent);background:var(--panel)}.trail-entry.off-path{opacity:.6}.trail-id{font:11px var(--mono);padding-top:3px;color:var(--accent);min-width:25px}.trail-entry strong{display:block;font-size:15px;font-weight:400}.trail-entry small{display:block;font:10px/1.8 var(--mono);color:var(--muted);margin-top:3px}.path-form{display:flex;gap:8px;margin:13px 0}.path-form input,.path-pair select,.path-switch select{min-width:0;background:var(--panel);color:var(--ink);border:1px solid var(--line);padding:10px;font:12px var(--mono);max-width:100%}.path-form input{flex:1}.path-switch{display:flex;gap:8px;margin:12px 0 20px}.path-switch select{flex:1}.path-pair{display:grid;grid-template-columns:1fr 1fr;gap:8px;margin:12px 0}.path-pair label{display:flex;flex-direction:column;font:11px var(--mono);gap:7px;min-width:0}.path-comparison{font-size:14px;color:var(--muted);margin-top:15px;overflow-wrap:anywhere}.path-comparison p+p{margin-top:8px}.session-files{padding-top:20px;margin-top:22px;border-top:1px solid var(--soft)}.file-button{position:relative;overflow:hidden;cursor:pointer}.file-button input{position:absolute;inset:0;opacity:0;width:100%;cursor:pointer}.file-button:focus-within{outline:3px solid var(--accent);outline-offset:4px}.data-facts{font:12px/1.8 var(--mono);color:var(--muted);margin-top:20px}.data-facts code{overflow-wrap:anywhere}.rama-note{font-size:15px;color:var(--muted);margin-top:16px}.rama-static-figure{margin-top:26px}.rama-static-figure img{width:100%;height:auto;border:1px solid var(--line);border-radius:8px;background:#1f2a26}.rama-static-figure figcaption{color:var(--muted);font-size:15px;margin-top:12px}.paper-source-note{font-size:14px;color:var(--muted);margin-top:18px}
@media(max-width:850px){.rama-main-grid{grid-template-columns:1fr}.rama-main-grid .rama-column:first-child{grid-row:1}.trail-layout{grid-template-columns:1fr}.rama-app{padding:16px}.rama-panel{padding:16px}.rama-metric{min-width:95px;padding:10px 14px}.rama-metric strong{font-size:25px}.rama-metrics{gap:8px}.rama-sequence{grid-template-columns:repeat(12,minmax(0,1fr))}.sequence-letter{min-height:35px;font-size:14px}.table-scroll{max-height:300px}}
@media(max-width:450px){.rama-app{padding:10px}.rama-panel{padding:12px}.rama-sequence{grid-template-columns:repeat(8,minmax(0,1fr))}.sequence-letter{min-height:36px}.motif-form{flex-wrap:wrap}.motif-form input{flex-basis:140px}.rama-panel-head{align-items:flex-start}.rama-panel-head h3{font-size:20px}.rama-metrics{display:grid;grid-template-columns:repeat(3,1fr)}.rama-metric{min-width:0;padding:10px}.rama-metric span{font-size:9px}.rama-controls .button,.session-files .button{font-size:11px;padding:9px 11px}.residue-table{font-size:11px}.residue-table td,.residue-table th{padding:5px}.path-form{flex-wrap:wrap}.path-form input{flex-basis:140px}}